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Ongewenste effecten -- Orthostatische hypotensie en duizeligheid, vooral bij ouderen en bij associatie met andere antihypertensiva.

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Chronic overdosage with any corticosteroid may result in signs or symptoms of hypercorticism (see PRECAUTIONS).

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Glucocorticoid therapy may be more effective following thymectomy and in patients having disease onset after 40 years of age.

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As sodium retention with resultant edema and potassium loss may occur in patients receiving corticosteroids, these agents should be used with caution in patients with congestive heart failure, hypertension, or renal insufficiency.

Corticosteroid therapy leads to a rise in hepatitis C virus (HCV) RNA levels which may eventually cause worsening of the underlying liver disease.

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Ultrasonography is also useful for orbital lesions and is used to look for orbital tumors, cysticercus, and foreign bodies.

NASONEX Nasal Spray, 50mcg, like other corticosteroids, should be used during pregnancy only if the potential benefits justify the potential risk to the fetus.

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To avoid drug-induced adrenal insufficiency, supportive dosage may be required in times of stress (such as trauma, surgery, or severe illness) both during treatment with Kenalog-40 Injection and for a year afterwards.

This negative impact of corticosteroids on growth has been observed at low systemic doses and in the absence of laboratory evidence of HPA axis suppression (ie, cosyntropin stimulation and basal cortisol plasma levels).

The medication arrests the release of chemicals in the body that causes inflammation.

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